RESEARCH ARTICLE


Strategy to Accelerate or Augment the Antidepressant Response and for An Early Onset of SSRI Activity. Adjunctive Amisulpride to Fluvoxamine in Major Depressive Disorder



Hardoy Maria Carolina*, Carta Mauro Giovanni
Department of Public Health, Centre for Research and Clinical Practice in Mental Health, Iglesias, University of Cagliari, Italy


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© Carolina and Giovanni; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Viale Merello 22, Cagliari, Italy; Tel: +39 3338452928; E-mail: mgcarta@tiscali.it


Abstract

The topic of early response to antidepressant treatment has been extensively studied in major depressive disorder (MDD). We serendipitous observed an increase tolerability, a rapid response to therapy and an early onset of antidepressant fluvoxamine activity when associated with amisulpride in patients with major depressive disorder. The purpose of this study was to investigate our preliminary observations.

Keywords: Antidepressant, major depressive disorder, community survey, epidemiology, lifetime prevalence.