The Perception of Physical Health Status in Obsessive-Compulsive Disorder: A Systematic Review and Meta-Analysis

Andrea Pozza1, Fabio Ferretti1, *, Anna Coluccia1
1 Department of Medical Sciences, Surgery and Neurosciences, Santa Maria alle Scotte University Hospital of Siena, viale Bracci 16, 53100 Siena, Italy

Article Metrics

CrossRef Citations:
Total Statistics:

Full-Text HTML Views: 909
Abstract HTML Views: 621
PDF Downloads: 307
ePub Downloads: 262
Total Views/Downloads: 2099
Unique Statistics:

Full-Text HTML Views: 534
Abstract HTML Views: 333
PDF Downloads: 210
ePub Downloads: 156
Total Views/Downloads: 1233

Creative Commons License
© 2019 Pozza et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: ( This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Medical Sciences, Surgery and Neurosciences, Santa Maria alle Scotte University Hospital Viale Bracci 16, 53100 Siena, Italy; Tel: +39 0577 586409; Fax: +39 0577 233222;



Physical Health Status is a neglected outcome in clinical practice with Obsessive-Compulsive Disorder (OCD) and a systematic review is lacking.


The current study presents the first systematic review and meta-analysis summarizing the evidence on (a) perceived Physical Health Status, Bodily Pain and Role Limitations due to Physical Problems in patients with OCD compared with controls, (b) age, gender, severity of OCD symptoms, study publication date, study methodological quality as moderators of perceived Physical Health Status.


Case-control studies were included if they (a) compared OCD patients with healthy/general population participants as controls, and (b) used validated self-report instruments. Two reviewers searched electronic databases, contacted corresponding authors, and examined reference lists/conference proceedings/theses.


Fourteen studies were included. A large significant negative effect size without publication bias showed that controls reported higher perceived Physical Health Status than patients with OCD. Medium and small effect sizes favouring controls emerged for Role Limitations due to Physical Problems and Bodily Pain, respectively. Higher age, females percentage, and publication date were associated with larger effect sizes; higher OCD severity and methodological quality were associated with smaller effect sizes.


Perceived Physical Health should be evaluated and addressed by clinicians during treatment, particularly with older, female and less severe patients. Lifestyle interventions might be implemented.

Keywords: Obsessive-Compulsive Disorder, Functioning, Physical Health, Systematic Review, Well-being, Pain, Lifestyle, Meta-analysis.